The Duke of Sussex, the Duke of Cambridge and the Prince of Wales will all attend talks on Monday
The Queen will meet senior royals in Sandringham later to discuss the future roles of the Duke and Duchess of Sussex.
Prince Harry, the Duke of Cambridge and the Prince of Wales will all attend the meeting, while Meghan is expected join the discussion by phone from Canada.
The Sussexes say they plan to step back as senior members of the Royal Family.
BBC royal correspondent Jonny Dymond said a deal “might take time”.
Prince Charles has returned from Oman for the talks after attending a condolence ceremony following the death of Sultan Qaboos bin Said Al Said.
Prince Harry is understood to be travelling to Sandringham from Frogmore Cottage, his home in Windsor.
It is hoped the talks will produce a “next step” on the way to defining the couple’s new relationship with the Royal Family – in line with the Queen’s wish to find a solution within days.
In their statement on Wednesday, the couple said they intend to “step back” as senior royals and work to become financially independent.
They also said they plan to split their time between the UK and North America, while “continuing to honour our duty to the Queen, the Commonwealth, and our patronages”.
Monday’s gathering at the Queen’s estate in Norfolk – being described as the “Sandringham summit” – will be the first time the monarch has come face-to-face with Prince Harry since the Sussexes’ announcement, which was posted on their official Instagram account.